Here are a few to pique your interest:
#5 – Simplify. Focus. Combine characters. Hop over detours. You’ll feel like you are losing valuable stuff but it sets you free.
#12 – Discount the 1st, 2nd, 3rd, 4th, 5th – get the obvious out of the way. Surprise yourself.
#21 – You gotta indentify with your situation/characters, can’t just write ‘cool.’ What would make YOU act that way.
Check out the rest of the rules in Imgur.
What would you add to the list?